Additional Information About the PHS Forms

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Notable Changes Made to PHS 398

  • Revisions have been made in the PHS 398, Part II, Human Subjects Research Supplement, to further address NIH implementation of OHRP Guidance on research involving coded private information or biological specimens. Notable changes in content have been marked in purple. Minor revisions and formatting changes have been made in the PHS 398, Parts I and III (1/20/05).
  • Chapter V of the PHS 398 has been revised to reflect that the modular budget format no longer applies to SBIR/STTR grant applications (1/14/05).
  • Significant revisions have been made in the PHS 398, Part II, Human Subjects Research Supplement, to address NIH implementation of OHRP Guidance on research involving coded private information or biological specimens. Notable changes in content have been marked in purple. Minor revisions and formatting changes have been made in the PHS 398, Parts I and III. On Form Page 3, Research Grant Table of Contents, the ordering of items in the Research Plan has been revised (12/30/04).
  • Page numbering on Form Page 2 and Form Page 2-continued has been changed to Page 2 and Page 3. Be sure to number all pages in application sequentially (11/23/04).
  • Clarification of font and format specifications (11/17/04).
  • New PHS 398 (Rev. 9/04) instructions and forms posted 11/02/2004. The 11/2/2004 NIH Guide Notice has important details regarding changes made to this version.