Alexandra Miller, PhD
Assistant Professor
Radiation Biology
4301 Jones Bridge Road
Bethesda MD 20814
Office: 301-295-9232
Fax: 301-295-1731
miller@afrri.usuhs.mil
Currently the research focus in my laboratory involves the following: characterizing the late effects of radiation and/or heavy metal exposures; developing medical countermeasures to radiation carcinogenesis, particularly agents that inhibit molecular chaperones like Hsp90 or inhibit histone deacetylase; and to understand mechanisms (genetic and epigenetic) of radiation late effects.
My specific research interests are radiation late effects, biomarkers of late effects, low-dose high-LET radiation, internal emitters, carcinogenesis, transgenerational effects, and epigenetic mechanisms.
Recent publications
- 2011—Miller AC, Lison P, Michel M, Merlot. Oral radioprotection by phenylbutyrate: Effects on human cells. International Journal Radiation Biology [in press].
- 2011—Miller AC, Cohen S, Stewart M, Rivas R, Lison P. Radiation protection by the histone deacetylase inhibitor phenylbutyrate. Radiat Environ Biophys. 50(4):585–96, 2011.
- 2011—Miller AC. Update on depleted uranium studies: In vitro and in vivo. World Health Organization Technical Report on Depleted Uranium, January 2011.
- 2010—Miller AC, Stewart M, Rivas R. Preconceptional paternal exposure to depleted uranium: Transmission of genetic damate to offspring. Health Physics 9(3):371–9, 2010.
- 2009—Miller AC, Stewart M, Rivas R, Merlot R, Lison P. DNA methylation during depleed uranium-induced leukemia. Biochimie. 91(10):1328–30, 2009.
- 2007—Miller AC. A review of depleted uranium health effects: In vivo and in vitro studies, Rev Environ Health 22(1):75–89, 2007.
- 2007—Miller AC, Stewart M, Rivas R, Marino S, Randers-Pehrson G, Shi L. Observation of radiation-specific damage in cells exposed to depleted uranium: hprt gene mutation frequency. Radiation Measurements 42(6–7):1029–1032, 2007.
- 2005—Miller AC, Stewart R Rivas M, Michel M, Merlot, R, Lison P. Leukemic transformation of hematopoietic cells in mice internally exposed to depleted uranium. Mol Cell Biochem. 279(1–2):97–104, 2005.
Books - 2006—Miller AC (Editor) Depleted Uranium: Properties, Uses, and Health Consequences. Boca Raton, London, New York: CRC Press, ISBN: 0849330475, 9780849330476. 2006.
Book chapters - Miller AC, Satyamitra M, Kulkarni, S. "Late and Low Level Effects of Ionizing Radiation", Textbook of Military Medicine, Bender Press, Washington, DC [in press].
- 2010—Miller AC. "Toxicology of Depleted Uranium, General and Applied Toxicology", John Wiley and Sons, London, UK, Jan. 2010.
Department
Research
Faculty
Graduate Education
AFRRI
Contact
Christopher R. Lissner, PhD, M(ASCP)
CAPT, MSC, USN Ret.
Scientific Director
Armed Forces Radiobiology Research
Institute & Acting Chair, Department
of Radiation Biology, School of Medicine,
Uniformed Services University
of the Health Sciences
Building 42, 8901 Wisconsin Avenue
Bethesda, Maryland 20889-5603
lissner@afrri.usuhs.mil
Tel 301-295-4995
FAX 301-295-4967
The image below is that of an announcement that appeared in Radiation Research, the official journal of the Radiation Research Society, for the USU PhD Program in Radiation Biology. Click the image to go to the home page of Radiation Research.
