Suzanne B. Bausch, Ph.D., Associate Professor
Ph.D., Pharmacology, University of Washington
Postdoctoral, Neurobiology, Duke
Email: sbausch@usuhs.mil
Bausch Lab Personnel
Synaptic alterations in epileptogenesis
Epileptogenesis is the process by which a normal brain becomes chronically prone to seizures. Many brain insults can induce epileptogenesis, but no therapies exist to prevent it. Reorganization of neuronal circuits and alterations in individual synapses are associated with epileptogenesis. Our research goals are to elucidate the extent, the functional consequences and the mechanisms underlying these synaptic alterations and to test potential anti-epileptogenic therapies.
To attain these goals, we use electrophysiology (whole-cell and extracellular), pharmacological manipulations, laser-evoked photolysis of caged compounds, immunohistochemistry and histology as well as in vivo and in vitro rodent models of traumatic brain injury, epileptogenesis and temporal lobe epilepsy.
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Uniformed Services University of the Health Sciences
Department of Pharmacology
4301 Jones Bridge Road
Bethesda, MD 20814
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