Merrell Laboratory
 

Morris Makobongo

Post-doctoral Fellow

USUHS, Department of Microbiology and Immunology

 Morris. Makobongo. CTR @ usuhs.mil

Education/Training

• M.S. and Ph.D. in Immunology, University of Queensland, Australia
   

Selected Publications

Makobongo M.O., Kovachi T., Gancz H., Mor A., Merrell D.S. In vitro antibacterial activity of acyl-lysyl oligomers against Helicobacter pylori. Antimicrob Agents Chemother. 2009 Oct;53(10):4231-9.

Klein MM, Gittis AG, Su HP, Makobongo MO, Moore JM, Singh S, Miller LH, Garboczi DN.  The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure.  PLoS Pathog. 2008 Sep 5;4(9):e1000147.

 Makobongo MO, Keegan B, Long CA, Miller LH.  Immunization of Aotus monkeys with recombinant cysteine-rich interdomain region 1 alpha protects against severe disease during Plasmodium falciparum reinfection.  J Infect Dis. 2006 Mar 1;193(5):731-40. Epub 2006 Jan 30.

 Fairhurst RM, Baruch DI, Brittain NJ, Ostera GR, Wallach JS, Hoang HL, Hayton K, Guindo A, Makobongo MO, Schwartz OM, Tounkara A, Doumbo OK, Diallo DA, Fujioka H, Ho M, Wellems TE.  Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria.  Nature. 2005 Jun 23;435(7045):1117-21.

 Makobongo MO, Riding G, Xu H, Hirunpetcharat C, Keough D, de Jersey J, Willadsen P, Good MF.  The purine salvage enzyme hypoxanthine guanine xanthine phosphoribosyl transferase is a major target antigen for cell-mediated immunity to malaria.  Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2628-33. Epub 2003 Feb 19.

Wipasa J, Xu H, Makobongo M, Gatton M, Stowers A, Good MF.  Nature and specificity of the required protective immune response that develops postchallenge in mice vaccinated with the 19-kilodalton fragment of Plasmodium yoelii merozoite surface protein 1.  Infect Immun. 2002 Nov;70(11):6013-20.

Xu H, Wipasa J, Yan H, Zeng M, Makobongo MO, Finkelman FD, Kelso A, Good MF.  The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection.  J Exp Med. 2002 Apr 1;195(7):881-92.